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    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_DA7EE84FA533A521FD8C864CBCB3F828" xlink:to="lab_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_DA7EE84FA533A521FD8C864CBCB3F828" xlink:type="arc" />
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_9FB0D7860CFD2182388A864CBCB363F5" xlink:type="locator" />
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_BA9A1101D0AE0A5530CA864CBCB325C7" xlink:type="locator" />
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    <link:label id="lab_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_FA5B70BAA3AD9370D9E9864CBCB3065B_terseLabel_en-US" xlink:label="lab_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_FA5B70BAA3AD9370D9E9864CBCB3065B" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Share-based compensation, expected dividend rate</link:label>
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_FA5B70BAA3AD9370D9E9864CBCB3065B" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_FA5B70BAA3AD9370D9E9864CBCB3065B" xlink:to="lab_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_FA5B70BAA3AD9370D9E9864CBCB3065B" xlink:type="arc" />
    <link:label id="lab_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_F38EBAA1D11D3376568B864CBCB32310_terseLabel_en-US" xlink:label="lab_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_F38EBAA1D11D3376568B864CBCB32310" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Share-based compensation, expected volatility rate</link:label>
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_F38EBAA1D11D3376568B864CBCB32310" xlink:type="locator" />
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    <link:label id="lab_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_FFF360B3517C66322169864CBCB301BB_terseLabel_en-US" xlink:label="lab_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_FFF360B3517C66322169864CBCB301BB" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Share-based compensation, expected term</link:label>
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_FFF360B3517C66322169864CBCB301BB" xlink:type="locator" />
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    <link:label id="lab_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_62A74720CE05F5641ED1864CBCB39EBD_terseLabel_en-US" xlink:label="lab_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_62A74720CE05F5641ED1864CBCB39EBD" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Share-based compensation, award vesting period</link:label>
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    <link:label id="lab_zts_ManufacturingResearchCorporateMember_C3A0A5CEA433ECB908A039496D8DFB04_documentation_en-US" xlink:label="lab_zts_ManufacturingResearchCorporateMember_C3A0A5CEA433ECB908A039496D8DFB04" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Manufacturing, Research, Corporate [Member]</link:label>
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_BusinessAcquisitionCostOfAcquiredEntityTransactionCosts" xlink:label="loc_us-gaap_BusinessAcquisitionCostOfAcquiredEntityTransactionCosts_8350EC7EF47EE254C32E39496D8F5D4A" xlink:type="locator" />
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    <link:label id="lab_zts_SeniorNotes3.250Due2021Member_005DC412B1319C956246864CBB52F022_label_en-US" xlink:label="lab_zts_SeniorNotes3.250Due2021Member_005DC412B1319C956246864CBB52F022" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Senior Notes 3.250% Due 2021 [Member]</link:label>
    <link:label id="lab_zts_SeniorNotes3.250Due2021Member_005DC412B1319C956246864CBB52F022_documentation_en-US" xlink:label="lab_zts_SeniorNotes3.250Due2021Member_005DC412B1319C956246864CBB52F022" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Senior Notes 3.250% Due 2021</link:label>
    <link:loc xlink:href="zts-20190930.xsd#zts_SeniorNotes3.250Due2021Member" xlink:label="loc_zts_SeniorNotes3.250Due2021Member_005DC412B1319C956246864CBB52F022" xlink:type="locator" />
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    <link:label id="lab_zts_SeniorNotesDue2023Member_53C21CD19B5B864824F8864CBB5305A6_label_en-US" xlink:label="lab_zts_SeniorNotesDue2023Member_53C21CD19B5B864824F8864CBB5305A6" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Senior Notes Due 2023 [Member]</link:label>
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    <link:label id="lab_zts_SeniorNotes4.500Due2025Member_B0097A117701006A48B5864CBB53A928_documentation_en-US" xlink:label="lab_zts_SeniorNotes4.500Due2025Member_B0097A117701006A48B5864CBB53A928" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Senior Notes Due 2025 [Member]</link:label>
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    <link:label id="lab_zts_SeniorNotes3.000Due2027Member_454B5209E9E1B8F527FA864CBB533E86_label_en-US" xlink:label="lab_zts_SeniorNotes3.000Due2027Member_454B5209E9E1B8F527FA864CBB533E86" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Senior Notes 3.000% Due 2027 [Member]</link:label>
    <link:label id="lab_zts_SeniorNotes3.000Due2027Member_454B5209E9E1B8F527FA864CBB533E86_documentation_en-US" xlink:label="lab_zts_SeniorNotes3.000Due2027Member_454B5209E9E1B8F527FA864CBB533E86" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Senior Notes 3.000% Due 2027</link:label>
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    <link:label id="lab_zts_SeniorNotes3.900Due2028Member_D82AAC3E5B59CC4076F0864CBB5376C1_documentation_en-US" xlink:label="lab_zts_SeniorNotes3.900Due2028Member_D82AAC3E5B59CC4076F0864CBB5376C1" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:type="resource" xml:lang="en-US">Senior Notes 3.900% Due 2028 [Member]</link:label>
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    <link:label id="lab_us-gaap_ShortTermLeasePayments_F95ACFB55543C27AC3C837B62F520EAC_terseLabel_en-US" xlink:label="lab_us-gaap_ShortTermLeasePayments_F95ACFB55543C27AC3C837B62F520EAC" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Short-term lease payments not included in the measurement of lease liabilities</link:label>
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    <link:label id="lab_us-gaap_OperatingLeasePayments_968217090D67E39ED96637B62F522DB7_terseLabel_en-US" xlink:label="lab_us-gaap_OperatingLeasePayments_968217090D67E39ED96637B62F522DB7" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Cash paid for amounts included in the measurement of lease liabilities</link:label>
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    <link:label id="lab_us-gaap_OperatingLeaseLiabilityCurrent_4D2564E0B8622AE9936837B62F5222CB_label_en-US" xlink:label="lab_us-gaap_OperatingLeaseLiabilityCurrent_4D2564E0B8622AE9936837B62F5222CB" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Operating Lease, Liability, Current</link:label>
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_983A313D789F40CB6D4037B62F527889" xlink:type="locator" />
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseLiability" xlink:label="loc_us-gaap_OperatingLeaseLiability_BC665EF53284398926E937B62F5352BB" xlink:type="locator" />
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    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_3A11DEA81CA85163907237B62F53F65B" xlink:type="locator" />
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    <link:label id="lab_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_F70297BB7E375DAE1C6437B62F53F0DF_terseLabel_en-US" xlink:label="lab_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_F70297BB7E375DAE1C6437B62F53F0DF" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Weighted-average discount rate&#8212;operating leases</link:label>
    <link:label id="lab_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_F70297BB7E375DAE1C6437B62F53F0DF_label_en-US" xlink:label="lab_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_F70297BB7E375DAE1C6437B62F53F0DF" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Operating Lease, Weighted Average Discount Rate, Percent</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_F70297BB7E375DAE1C6437B62F53F0DF" xlink:type="locator" />
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    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_AA38A3CC91A1D24D424537B62F533670_terseLabel_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_AA38A3CC91A1D24D424537B62F533670" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2019</link:label>
    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_AA38A3CC91A1D24D424537B62F533670_label_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_AA38A3CC91A1D24D424537B62F533670" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Lessee, Operating Lease, Liability, Payments, Due Next Twelve Months</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_AA38A3CC91A1D24D424537B62F533670" xlink:type="locator" />
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    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_D462F2DD1B2BF711DEC737B62F53EAD6_terseLabel_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_D462F2DD1B2BF711DEC737B62F53EAD6" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2020</link:label>
    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_D462F2DD1B2BF711DEC737B62F53EAD6_label_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_D462F2DD1B2BF711DEC737B62F53EAD6" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Lessee, Operating Lease, Liability, Payments, Due Year Two</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_D462F2DD1B2BF711DEC737B62F53EAD6" xlink:type="locator" />
    <link:labelArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_D462F2DD1B2BF711DEC737B62F53EAD6" xlink:to="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_D462F2DD1B2BF711DEC737B62F53EAD6" xlink:type="arc" />
    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_38250B26FB445FBE583637B62F53ABC7_terseLabel_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_38250B26FB445FBE583637B62F53ABC7" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2021</link:label>
    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_38250B26FB445FBE583637B62F53ABC7_label_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_38250B26FB445FBE583637B62F53ABC7" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Lessee, Operating Lease, Liability, Payments, Due Year Three</link:label>
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2019/elts/us-gaap-2019-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_38250B26FB445FBE583637B62F53ABC7" xlink:type="locator" />
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    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_3E4972D2808491BB87DD37B62F542999_terseLabel_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_3E4972D2808491BB87DD37B62F542999" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2022</link:label>
    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_3E4972D2808491BB87DD37B62F542999_label_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_3E4972D2808491BB87DD37B62F542999" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Lessee, Operating Lease, Liability, Payments, Due Year Four</link:label>
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    <link:label id="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_2ACF4D166561AB71329937B62F54D122_terseLabel_en-US" xlink:label="lab_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFive_2ACF4D166561AB71329937B62F54D122" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">2023</link:label>
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    <link:label id="lab_us-gaap_ProceedsFromHedgeInvestingActivities_AAA82F6B3B589282C29E391392D145C1_terseLabel_en-US" xlink:label="lab_us-gaap_ProceedsFromHedgeInvestingActivities_AAA82F6B3B589282C29E391392D145C1" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:type="resource" xml:lang="en-US">Net proceeds on swaps designated as net investment hedges</link:label>
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    <link:label id="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_30E020D15FB686A1CBD637EC392266AD_totalLabel_en-US" xlink:label="lab_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_30E020D15FB686A1CBD637EC392266AD" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:type="resource" xml:lang="en-US">Income before provision for taxes on income</link:label>
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    <link:label id="lab_us-gaap_ShorttermDebtFairValue_3145A590100456274608864CBA93DA45_label_en-US" xlink:label="lab_us-gaap_ShorttermDebtFairValue_3145A590100456274608864CBA93DA45" xlink:role="http://www.xbrl.org/2003/role/label" xlink:type="resource" xml:lang="en-US">Short-term Debt, Fair Value</link:label>
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